منابع مشابه
Ocular toxicity of hydroxychloroquine.
OBJECTIVES To review the types, incidence, pathogenesis, risk factors, and clinical characteristics of hydroxychloroquine ocular toxicity and current views about its screening and management. DATA SOURCES Literature search of Medline up to May 2005. STUDY SELECTION Key words for the literature search were 'hydroxychloroquine', 'chloroquine', 'ocular', 'toxicity', 'retinopathy', and 'screeni...
متن کاملOcular toxicity and hydroxychloroquine: guidelines for screening.
Chloroquine and hydroxychloroquine (4-aminoquinolones) are used by dermatologists for the treatment of a wide range of disorders. It is widely recognized that their use may lead to ocular complications, but policies for ophthalmological screening and follow-up vary widely. In this article, the current literature on the ocular complications of antimalarials is reviewed, together with the results...
متن کاملRetinal toxicity associated with chronic exposure to hydroxychloroquine and its ocular screening. Review
Hydroxychloroquine sulfate (HCQ, Plaquenil) is an analogue of chloroquine (CQ), an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Because it presents potential secondary effects including irreversible maculopathy, kno...
متن کاملComparison of screening procedures in hydroxychloroquine toxicity.
OBJECTIVES To compare different screening procedures for hydroxychloroquine sulfate (Plaquenil) toxicity at different stages of damage. METHODS Ten patients were studied using 10-2 automated fields, multifocal electroretinography, spectral domain optical coherence tomography (SD-OCT), and fundus autofluorescence. RESULTS All 10 patients used hydroxychloroquine for more than 6 years, and tho...
متن کاملOcular toxicity and functional vision recovery in a patient treated with hydroxychloroquine.
CASE REPORT We report the case of a 64-year-old woman with rheumatoid arthritis and Sjögren's syndrome, treated during 48 months with hydroxychloroquine that was removed after an ophthalmological evaluation showed bilateral vision loss associated with paracentral scotoma in the visual field, fundoscopic macular pigmentary changes, and severely impaired central multifocal electrorretinogram (mfE...
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ژورنال
عنوان ژورنال: Revista Paraguaya de Reumatología
سال: 2019
ISSN: 2413-4341
DOI: 10.18004/rpr/2019.05.02.63-69